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Publikationen AG Prof. Fischer

der folgenden Jahre:

2014    2013    2012    2011    2010  

2009    2008    2007    2006    2005    

2004    2003    2002    2001    2000 



Ernst J, Grabiec U, Greither T, Fischer B, Dehghani F. (2016) The endocannabinoid system in the human granulosa cell line KGN. Mol Cell Endocrinol. doi: 10.1016/j.mce.2016.01.006. [Epub ahead of print]


Gürke J, Hirche F, Thieme R, Haucke E, Schindler M, Stangl G, Fischer B, Navarrete Santos A. (2015) Maternal diabetes leads to adaptation in embryonic amino acid metabolism during early pregnancy. PLOS ONE. 10(5):e0127465

Klöting N, Hesselbarth N, Gericke M, Kunath A, Biemann R, Chakaroun R, Kosacka J, Kovacs P, Kern M, Stumvoll M, Fischer B, Rolle-Kampczyk U, Feltens R, Otto W, Wissenbach DK, von Bergen M, Blüher M. (2015) Di-(2-Ethylhexyl)-Phthalate (DEHP) Causes Impaired Adipocyte Function and Alters Serum Metabolites. PLoS One. 10(12):e0143190

Schaedlich K, Schmidt JS, Kwong WY, Sinclair KD, Kurz R, Jahnke HG, Fischer B. (2015) Impact of di-ethylhexylphthalate (DEHP) exposure on metabolic programming in P19-ECC derived cardiomyocytes. J Appl Toxicol. 35:861-869


Biemann R, Fischer B, Blüher M, Navarrete Santos A (2014) Tributyltin affects adipogenic cell fate commitment in mesenchymal stem cells by a PPARgamma independent mechanism. Chem-Biol Interact. 214:1-9.

Biemann R, Fischer B, Navarrete Santos A (2014) Adipogenic Effects of a Combination of the Endocrine-Disrupting Compounds Bisphenol A, Diethylhexylphthalate, and Tributyltin. Obesity Facts. 7:48-56.

Ernst J, Jann JC, Biemann R, Koch HM, Fischer B (2014) Effects of the environmental contaminants DEHP and TCDD on estradiol synthesis and aryl hydrocarbon receptor and peroxisome proliferator-activated receptor signalling in the human granulosa cell line KGN. Mol Hum Reprod. 20:919-928.

Haucke E, Navarrete Santos Al, Simm A, Henning C, Glomb M, Guerke J, Schindler M, Fischer B, Navarrete Santos An (2014) Accumulation of advanced glycation end products in the rabbit blastocyst under maternal diabetes. Reproduction. 148:169-178.

Haucke E, Navarrete Santos Al, Simm A, Silber R-E, Hofmann B (2014) Glycation of extracellular matrix proteins impairs migration of immune cells. Wound Repair Regen. 22:239–245.

Ott C, Jacobs K, Haucke E, Navarrete Santos A, Grune T, Simm A (2014) Role of Advanced Glycation End Products in Cellular Signaling. Redox Biology. 2:411-429.

Schicht M, Ernst J, Nielitz A, Fester L, Tsokos M, Guddat SS, Bräuer L, Bechmann J, Delank KS, Wohlrab D, Paulsen F, Claassen H (2014) Articular cartilage chondrocytes express aromatase and use enzymes involved in estrogen metabolism. Arthritis Res Ther. 16: R93.

Schindler M, Pendzialek M, Navarrete Santos Al, Plösch T, Seyring S, Gürke J, Haucke E, Knelangen JM, Fischer B and Navarrete Santos An (2014) Maternal diabetes leads to unphysiological high lipid accumulation in rabbit preimplantation embryos. Endocrinology. 155:1498-1509.

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Schindler M, Fischer S, Thieme R, Fischer B, Navarrete Santos A. (2013) cAMP-responsive element binding protein: a vital link in embryonic hormonal adaptation. Endocrinology. 154:2208-2221.

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Biemann, R., Navarrete Santos, An., Navarrete Santos, Al., Riemann, D., Knelangen, J., Blüher, M., and Fischer B. (2012) Endocrine disrupting chemicals affect the adipogenic differentiation of mesenchymal stem cells in distinct ontogenetic windows. Biochem Biophys Res Commun. 417:747-752.

Duranthon V, Beaujean N, Brunner M, Odening KE, Santos AN, Kacskovics I, Hiripi L, Weinstein EJ, Bosze Z. (2012) On the emerging role of rabbit as human disease model and the instrumental role of novel transgenic tools.Transgenic Res. 21(4):699-713.

Fowler, P.A., Bellingham, M., Sinclair, K.D., Evans, N.P., Pocar, P., Fischer, B., Schaedlich, K., Schmidt, J.-S., Amezaga, M.R., Bhattacharya, S., Rhind, S.M., O'Shaughnessy, P.J. (2012) Impact of endocrine-disrupting compounds (EDCs) on female reproductive health. Mol Cell Endocrinol. 355:231-239.

Knelangen, J.M., Kurz, R., Schagdarsurengin, U., Fischer, B., Navarrete Santos, A. (2012) Short-time glucose exposure of embryonic carcinoma cells impairs their function as terminally differentiated cardiomyocytes. Biochem Biophys Res Commun. 420:230-235.

Königsdorf, C.A.I., Navarrete Santos, A., Schmidt, J.-S., Fischer, S., and Fischer, B. (2012) Expression profile of fatty acid metabolism genes in preimplantation blastocysts of obese and non-obese mice. Obesity Facts. 5:575–586.

Llobat, L., Marco-Jiménez, F., Peñaranda, D.S., Thieme, R., Navarrete Santos, A. and Vicente, J.S. (2012) mRNA expression in rabbit blastocyst and endometrial tissue of candidate gene involved in gestational losses. Reprod Dom Anim. 47:281-287.

Pocar, P., Fiandanese, N., Secchi, C., Berrini, A., Fischer, B., Schmidt, J.-S., Schaedlich, K., Borromeo, V. (2012) Exposure to di(2-ethyl-hexyl) phthalate (DEHP) in utero and during lactation causes long-term pituitary-gonadal axis disruption in mouse male and female offspring. Endocrinology. 153:937-948.

Pocar, P., Fiandanese, N., Secchi, C., Berrini, A., Fischer, B., Schmidt, J.-S., Schaedlich, K., Rhind, S. M., Zhang, Z., Borromeo, V. (2012) Effects of polychlorinated biphenyls in CD-1 mice: reproductive toxicity and intergenerational transmission. Toxicol Sci. 126:213-226.

Schmidt, J.-S., Schaedlich, K., Fiandanese, N., Pocar, P., and Fischer, B. (2012) Effects of Di(2-ethylhexyl) Phthalate (DEHP) on Female Fertility and Adipogenesis in C3H/N mice. Environmental Health Perspectives. 120:1123-1129.

Thieme, R., Ramin, N., Fischer, S., Püschel, B., Fischer, B., and Navarrete Santos, A., (2012) Gastrulation in rabbit blastocysts depends on insulin and the insulin-like-growth-factor 1. Mol Cell Endocrinol. 348:112-119.

Thieme, R., Schindler, M., Ramin, N., Fischer, S., Mühleck, B., Fischer, B., Navarrete Santos, A. (2012) Insulin growth factor adjustment in preimplantation rabbit blastocysts and uterine tissues in response to maternal type 1 diabetes. Mol Cell Endocrinol. 358:96-103.

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Horling, K., Navarrete Santos, A., and Fischer, B. (2011) The AhR is constitutively activated and affects granulosa cell features in the human cell line KGN. Mol Hum Reprod. 17:104-114. 

Knelangen, J., van der Hoek, M., Kong, W.-C., Owens, J., Fischer, B., and Navarrete Santos, A. (2011) MicroRNA expression profile during adipogenic differentiation in mouse embryonic stem cells. Physiol Genomics. 43:611-620. 

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Fischer, S., Navarrete Santos, A., Thieme, R., Ramin, N., and Fischer, B. (2010) Adiponectin stimulates glucose uptake in rabbit blastocysts. Biol Reprod. 83:859-865.

Ramin, N., Thieme, R., Fischer, S., Schindler, M., Schmidt, T., Fischer, B., and Navarrete Santos, A. (2010) Maternal diabetes impairs gastrulation and insulin and IGF1 receptor expression in rabbit blastocysts. Endocrinology. 151:4158-4167. 

Schaedlich, K., Knelangen, J., Navarrete Santos, A., Fischer, B., and Navarrete Santos, A. (2010) A simple method to sort ESC-derived adipocytes. Cytometry: Part A. 77A:990-995. 

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Seifert, A., Rau, S., Küllertz, G, Fischer, B., Navarrete Santos, A. (2009) TCDD induces cell migration via NFATc1/ATX- signaling in MCF-7 cells. Toxicol Lett. 184:26-32.  

Seifert, A., Taubert, H., Hombach-Klonisch, S., Fischer, B., Navarrete Santos, A. (2009) TCDD mediates inhibition of p53 and activation of ERα signaling in MCF-7 cells at moderate hypoxic conditions. Int J Oncol. 35:417-424. 

Tonack, S., Ramin, N., Garimella S, Rao R, Seshagiri PB, Fischer B, Navarrete Santos A: (2009) Expression of glucose transporter isoforms and of the insulin receptor during hamster preimplantation embryo development. Ann Anat. 191:485-495. 

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Navarrete Santos, A., Ramin, N., Tonack, S., Fischer, B. (2008) Cell lineage-specific signalling of insulin and insulin like growth factor (IGF) 1 in rabbit blastocysts. Endocrinology. 149:515-524. 

Rao, R. P., Fischer, B., Seshagiri, P.B. (2008) Embryo-endometrial expression of leukaemia inhibitory factor in the golden hamster: increased expression during proestrous and window of implantation stages. Reprod Fertil Dev. 20:440-449. 

Schmidt, T., Fischer, S., Tsikolia, N., Navarrete Santos, A., Rohrbach, S., Ramin, N., Thieme, R., Fischer, B. (2008) Expression of adipokines in preimplantation rabbit and mice embryos. Histochem Cell Biol. 129:817-825. 

Seifert, A., Katschinski, D.M., Tonack, S., Fischer, B., Navarrete Santos, A. (2008) Significance of prolyl hydroxylase 2 in the interference of aryl hydrocarbon receptor (AhR) and hypoxia-inducible factor-1α (HIF-1α) signalling. Chem Res Toxicol. 21:341-348. 

Sireesha, G.V., Mason, R.W., Hassanein, M., Tonack, S., Navarrete Santos, A., Fischer, B., Seshagiri, P.B. (2008) Role of cathepsins in blastocyst hatching in the golden hamster. Mol Hum Reprod. 14:337-346. 

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Harvey, A.J., Navarrete Santos, A., Kirstein, M., Kind, K.L., Fischer, B., Thompson, J.G. (2007) Differential expression of oxygen-regulated genes in bovine blastocysts. Mol Reprod Dev. 74:290-299. 

Nestler, D., Risch, M., Fischer, B., Pocar, P. (2007) Regulation of aryl hydrocarbon receptor (AhR) activity in porcine cumulus-oocyte complexes in physiological and toxicological conditions: the role of follicular fluid. Reproduction. 133:887-897. 

Tonack, S., Kind, K., Thompson, J.G., Wobus, A.M., Fischer, B., Navarrete Santos, A. (2007) Dioxin affects glucose transport via the arylhydrocarbon receptor signal cascade in pluripotent embryonic carcinoma cells. Endocrinology. 148:5902-5959.

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Tonack, S., Rolletschek, A., Wobus, A., Fischer, B., Navarrete Santos, A. (2006) Differential expression of glucose transporter isoforms during embryonic stem cell differentiation. Differentiation. 74:499-509.

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Clausen, I., Kietz, S., Fischer, B. (2005) Lineage-specific effects of polychlorinated biphenyls (PCB) on gene expression in the rabbit blastocyst. Reprod Toxicol. 20:47-56. 

Pocar, P., Nestler, D., Risch, M., Fischer, B. (2005) Apoptosis in bovine cumulus-oocyte complexes after exposure to polychlorinated biphenyl mixtures during in vitro maturation. Reproduction. 130:857-868.

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Navarrete Santos, A., Tonack, S., Kirstein, M., Kietz, S., Fischer, B. (2004) Two insulin-responsive glucose transporter isoforms and the insulin receptor are developmentally expressed in rabbit preimplantation embryos. Reproduction. 128:503-516. 

Navarrete Santos, A., Tonack, S., Kirstein, M., Pantaleon, M., Kaye, P., Fischer, B. (2004) Insulin acts via mitogen-activated protein kinase phosphorylation in rabbit blastocysts. Reproduction. 128:517-526. 

Pocar, P., Augustin, R., Fischer, B. (2004) Constitutive expression of CYP1A1 in bovine cumulus oocyte-complexes in vitro: mechanisms and biological implications. Endocrinology. 145:1594-1601.

Tonack, S., Fischer, B., Navarrete Santos, A. (2004) Expression of the insulin-responsive glucose transporter isoform 4 in blastocysts of C57/BL6 mice. Anat Embryol. 208:225-230.

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Augustin, R., Pocar, P., Wrenzycki, C., Niemann, H., Fischer, B. (2003) Mitogenic and anti-apoptotic activity of insulin on bovine embryos produced in vitro. Reproduction. 126:91-99. 

Brylla, E., Tscheudschilsuren, G., Navarrete Santos, A., Nieber, K., Spanel-Borowski, K., Aust, G. (2003) Differences between retinal and choroidal microvascular endothelial cells (MVECs) under normal and hypoxic conditions. Exp Eye Res. 77:527-535. 

Fischer, B., Navarrete Santos, A. (2003) Glukose, Insulin und Glukosetransporter: Bedeutung und Weichenstellung für die Embryonalentwicklung. Reproduktionsmedizin. 19:195-201. 

Fischer, B., Pabst, R. (2003) Anatomie: Nadelöhr für die Medizinerausbildung. Deutsches Ärzteblatt. 100:A1659-1661. 

Hasan, A., Fischer, B. (2003) Epithelial cells in the oviduct and vagina and steroid-synthesizing cells in the rabbit ovary express AhR and ARNT. Anat Embryol. 207:9-18. 

Hombach-Klonisch, S., Hoang-Vu, C., Kehlen, A., Hinze, R., Holzhausen, H.J., Weber, E., Fischer, B., Dralle, H., Klonisch, T. (2003) INSL-3 is expressed in human hyperplastic and neoplastic thyrocytes. Int J Oncol. 22:993-1001. 

Kania, G., Blyszczuk, P., Czyz, J., Navarrete Santos, A., Wobus, A.M. (2003) Differentiation of mouse embryonic stem cells into pancreatic and hepatic cells. Method Enzymol. 365:287-303. 

Kietz, S., Fischer, B. (2003) Polychlorinated biphenyls affect gene expression in the rabbit preimplantation embryo. Mol Reprod Dev. 64:251-260. 

Pocar, P., Augustin, R., Gandolfi, F., Fischer, B. (2003) Toxic effects of in vitro exposure to p-tert-octylphenol on bovine oocyte maturation and developmental competence. Biol Reprod. 69:462-468. 

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Gandolfi, F., Pocar, P., Brevini, T.A., Fischer, B. (2002) Impact of endocrine disrupters on ovarian function and embryonic development. Domest Anim Endocrin. 23:189-201. 

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Augustin, R., Pocar, P., Navarrete Santos, A., Wrenzycki, C., Gandolfi, F., Niemann, H., Fischer, B. (2001) Glucose transporter expression is developmentally regulated in in vitro derived bovine preimplantation embryos. Mol Reprod Dev. 60:370-376. 

Hasan, A., Fischer, B. (2001) Hormonal control of arylhydrocarbon receptor (AhR) expression in the preimplantation rabbit uterus. Anat Embryol. 204:189-196. 

Hombach-Klonisch, S., Seeger, S., Tscheudschilsuren, G., Buchmann, J., Huppertz, B., Seliger, G., Fischer, B., Klonisch, T. (2001) Cellular localization of human relaxin-like factor in the cyclic endometrium and placenta. Mol Hum Reprod. 7:349-356. 

Klonisch, T., Fröhlich, C., Tetens, F., Fischer, B., Hombach-Klonisch, S. (2001) Molecular remodeling of members of the relaxin family during primate evolution. Mol Biol Evol. 18:393-403.

Klonisch, T., Kauffold, J., Steger, K., Bergmann, M., Leiser, R., Fischer, B., Hombach-Klonisch, S. (2001) Canine relaxin-like factor: unique molecular structure and differential expression within reproductive tissues of the dog. Biol Reprod. 64:442-450. 

Klonisch, T., Wolf, P., Hombach-Klonisch, S., Vogt, S., Küchenhoff, A., Tetens, F., Fischer, B. (2001) Epidermal growth factor-like ligands and erbB genes in the peri-implantation rabbit uterus and blastocyst. Biol Reprod. 64:1835-1844. 

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Hombach-Klonisch, S., Abd-Elaeim, M., Skidmore, J.A., Leiser, R., Fischer, B., Klonisch, T. (2000) Ruminant relaxin in the pregnant one-humped camel (Camelus dromedarius). Biol Reprod. 62:839-846.

Hombach-Klonisch, S., Buchmann, J., Sarun, S., Fischer, B., Klonisch, T. (2000) Relaxin-like factor (RLF) is differentially expressed in the normal and neoplastic human mammary gland. Cancer. 89:2161-2168. 

Hombach-Klonisch, S., Kauffold, J., Rautenberg, T., Steger, K., Tetens, F., Fischer, B., Klonisch, T. (2000) Relaxin-like factor (RLF) mRNA expression in the fallow deer. Mol Cell Endocrinol. 159:147-158. 

Navarete Santos, A., Augustin, R., Lazzari, G., Galli, C., Sreenan, J.M., Fischer, B. (2000) The insulin-dependent glucose transporter isoform 4 is expressed in bovine blastocysts. Biochem Bioph Res Co. 271:753-760. 

Navarrete Santos, A., Körber, S., Kullertz, G., Fischer, G., Fischer, B. (2000) Oxygen stress increases prolyl cis/trans isomerase activity and expression of cyclophilin 18 in rabbit blastocys. Biol Reprod. 62:1-7. 

Tetens, F., Kliem, A., Tscheudschilsuren, G., Navarrete Santos, A., Fischer, B. (2000) Expression of proto-oncogenes in bovine preimplantation blastocysts. Anat Embryol. 201:349-355.

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Fischer, B. (2000) Receptor-mediated effects of chlorinated hydrocarbons. Andrologia. 32:279-283. 

Fischer, B., Navarrete Santos A. (2003) Glukose, Insulin und Glukosetransporter: Bedeutung und Weichenstellungen für die Embryonalentwicklung. Reproduktionsmedizin. 19:195-201. 

Fischer, B., Pabst, R. (2003) Anatomie: Nadelöhr für die Medizinerausbildung. Dtsch Ärztebl. 100:A1659-1661. 

Pocar, P., Brevini, T.A.L. Fischer, B., Gandolfi, F. (2003) The impact of endocrine disruptors on oocyte competence. Reproduction. 125:313-325. 

Pocar, P., Fischer, B., Klonisch, T., Hombach-Klonisch, S. (2005) Molecular interactions of the aryl hydrocarbon receptor and its biological and toxicological relevance for reproduction. Reproduction. 129:379-389. 

Fischer, B., Navarrete Santos A., Ramin, N., Schmidt, T. (2008) Die Xenobiotika-Exposition stellt ein zu wenig beachtetes Risiko der Embryonalentwicklung vor der Implantation dar. J Reproduktionsmed Endokrinol. 5:4-9. 

Rhind, S.M., Evans, N.P., Bellingham, M., Sharpe, R.M., Cotinot, C., Mandon-Pepin, B., Loup, B., Fischer, B., van der Zalm, E., Hart, K., Schmidt, J-S., Amezaga, M.R., Sinclair, K.D., Lea, R.G., Pocar, P., Fischer, B., Fowler, P.A. (2010) Effects of pollutants on the reproduction and welfare of ruminants. Animal. 4:1227-1239.

Duranthon V, Beaujean N, Brunner M, Odening KE, Navarrete Santos A, Kacskovics I, Hiripi L, Weinstein EJ, Bosze Z. (2012) On the emerging role of rabbit as human disease model and the instrumental role of novel transgenic tools. Transgenic Res. 21(4):699-713.

Fischer, B., Pascale Chavatte-Palmer, P., Christoph Viebahn, C.,Navarrete Santos, A., Duranthon, V. (2012) Rabbit as a reproductive model for human health. Invited review. Reproduction. 144:1-10.

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