Notfälle
Blutspende
Karriere
Presse
Forschung
Lehre
Patienten
Zuweiser

Publikationen

2017

 

Weiss M (2017) Empirical models for fitting of oral concentration time curves with and without an intravenous reference. J Pharmacokinet Pharmacodyn. doi: 10.1007/s10928-017-9507-3. [abstract

 

Gergs U, Fahrion CM, Bock P, Fischer M, Wache H, Hauptmann S, Schmitz W, Neumann J (2017) Evidence for a functional role of calsequestrin 2 in mouse atrium. Acta Physiol (Oxf) 219(3): 669-682 [abstract

 

2016

 

Tadken T, Weiss M, Modess C, Wegner D, Roustom T, Neumeister C, Schwantes U, Schulz HU, Weitschies W, Siegmund W (2016) Trospium chloride is absorbed from two intestinal "absorption windows" with different permeability in healthy subjects. Int J Pharm 515(1-2): 367-373 [abstract

 

Weiss M (2016) Comparison of distributed and compartmental models of drug disposition: assessment of tissue uptake kinetics. J Pharmacokinet Pharmacodyn 43(5): 505-512 [abstract

 

Siebert N, Eger C, Seidel D, Jüttner M, Zumpe M, Wegner D, Kietz S, Ehlert K, Veal GJ, Siegmund W, Weiss M, Loibner H, Ladenstein R, Lode HN (2016) Pharmacokinetics and pharmacodynamics of ch14.18/CHO in relapsed/refractory high-risk neuroblastoma patients treated by long-term infusion in combination with IL-2. MAbs 8(3): 604-616 [abstract

 

Weiss M, Tura A, Kautzky-Willer A, Pacini G, D'Argenio DZ (2016) Human insulin dynamics in women: a physiologically based model. Am J Physiol Regul Integr Comp Physiol 310(3): R268-74 [abstract

 

2015

 

Hoehn M, Zhang Y, Xu J, Gergs U, Boknik P, Werdan K, Neumann J, Ebelt H (2015) Overexpression of protein phosphatase 2A in a murine model of chronic myocardial infarction leads to increased adverse remodeling but restores the regulation of β-catenin by glycogen synthase kinase 3β. Int J Cardiol 183: 39-46 [abstract

 

Weiss M, Krejcie TC, Avram MJ (2015) Beta blockade increases pulmonary and systemic transit time heterogeneity: evaluation based on indocyanine green kinetics in healthy volunteers. Clin Physiol Funct Imaging. doi: 10.1111/cpf.12295. [abstract

 

Weiss M, Sermsappasuk P, Siegmund W (2015) Modeling the heterogeneous intestinal absorption of propiverine extended-release. Eur J Pharm Sci 76: 133-137. doi: 10.1016/j.ejps.2015.05.010. [abstract

 

Weiss M (2015) Modeling accelerated and decelerated drug release in terms of fractional release rate. Eur J Pharm Sci 68: 51-55 [abstract

 

Thorling CA, Jin L, Weiss M, Crawford D, Liu X, Burczynski FJ, Liu D, Wang H, Roberts MS (2015) Assessing steatotic liver function after ischemia-reperfusion injury by in vivo multiphoton imaging of fluorescein disposition. Drug Metab Dispos 43(1): 154-162 [abstract

 

2014 

Gergs U, Clauss T, Ihlefeld D, Weiss M, Pönicke K, Hofmann GO, Neumann J (2014) Pharmacokinetics of ceftriaxone in plasma and bone of patients undergoing hip or knee surgery. J Pharm Pharmacol 66: 1552-1558 [abstract]

Gergs U, Simm A, Bushnaq H, Silber RE, Neumann J (2014) A positive inotropic effect of UTP in the human cardiac atrium. Eur J Pharmacol 724: 24-30 [abstract]

Paul M, Meyborg M, Boknik P, Gergs U, Gerss J, Schmitz W, Breithardt G, Wichter T, Neumann J (2014) Autonomic Dysfunction in Patients with Arrhythmogenic Right Ventricular Cardiomyopathy: Biochemical Evidence of Altered Signaling Pathways. Pacing Clin Electrophysiol 37: 173-178 [abstract]

Weiss M (2014) Exponential tails of drug disposition curves: Reality or appearance? J Pharmacokinet Pharmacodyn 41: 49-54 [abstract]

Weiss M, Arendt P, Hassna R (2014) Effect of disease states on α1-adrenoceptor binding and signal transduction parameters in isolated perfused heart: quantification by pharmacokinetic-pharmacodynamic modelling. J Pharm Pharmacol 66: 668-676 [abstract]

Weiss M, Kriangkrai W, Sungthongjeen S (2014) An empirical model for dissolution profile and its application to floating dosage forms. Eur J Pharm Sci 56: 87-91 [abstract

2013

Fuchs S, Neumann J, Klement A (2013) Arzneimittelüberwachung: Potenziell lebensrettend. DTSCH ARZTEBL 110: A2070-A2074 [abstract]

Gergs U, Böckler A, Ebelt H, Hauptmann S, Keller N, Otto V, Pönicke K, Schmitz W, Neumann J (2013) Human 5-HT4 receptor stimulation in atria of transgenic mice. Naunyn Schmiedebergs Arch Pharmacol 386: 357-367 [abstract]

Schreier B, Rabe S, Schneider B, Bretschneider M, Rupp S, Ruhs S, Neumann J, Rueckschloss U, Sibilia M, Gotthardt M, Grossmann C, Gekle M (2013) Loss of epidermal growth factor receptor in vascular smooth muscle cells and cardiomyocytes causes arterial hypotension and cardiac hypertrophy. Hypertension 61: 333-340 [abstract]

Weiss M (2013) Fractal structure of the liver: effect on drug elimination. J Pharmacokinet Pharmacodyn 40: 11-14 [abstract]

Weiss M, Liu X, Thorling CA, Roberts MS (2013) Functional characterization of hepatic transporters using intravital microscopy. Eur J Pharm Sci 49: 845-849 [abstract]

2012

Froese A, Breher SS, Waldeyer C, Schindler RFR, Nikolaev VO, Rinné S, Wischmeyer E, Schlueter J, Becher J, Simrick S, Vauti F, Kuhtz J, Meister P, Kreissl S, Torlopp A, Liebig SK, Laakmann S, Müller TD, Neumann J, Stieber J, Ludwig A, Maier SK, Decher N, Arnold HH, Kirchhof P, Fabritz L, Brand T (2012) Popeye domain containing proteins are essential for stress-mediated modulation of cardiac pacemaking in mice. J Clin Invest 122: 1119-1130 [abstract]

Gergs U, Boknik P, Buchwalow IB, Fabritz L, Gründker N, Kucerova D, Matus M, Werner F, Schmitz W, Neumann J (2012) Modulation of cardiac contractility by serine/threonine protein phosphatase type 5. Int J Cardiol 154: 116-121 [abstract]

Kucerová D, Baba HA, Bokník P, Fabritz L, Heinick A, Mát'us M, Müller FU, Neumann J, Schmitz W, Kirchhefer U (2012) Modulation of SR Ca2+ release by the triadin-to-calsequestrin ratio in ventricular myocytes. Am J Physiol Heart Circ Physiol 302: H2008-H2017 [abstract]

Liu X, Kruger PS, Weiss M, Roberts MS (2012) The pharmacokinetics and pharmacodynamics of cisatracurium in critically ill patients with severe sepsis. Brit J Clin Pharmacol 73(5): 741-749 [abstract]

Peschke E, Hofmann K, Pönicke K, Wedekind D, Mühlbauer E (2012) Catecholamines are the key for explaining the biological relevance of insulin-melatonin antagonisms in type 1 and type 2 diabetes. J Pineal Res 52: 389-396 [abstract]

Pönicke K, Gergs U, Buchwalow IB, Hauptmann S, Neumann J (2012) On the presence of serotonin in mammalian cardiomyocytes. Mol Cell Biochem 365: 301-312 [abstract]

Scheller C, Vogel AS, Simmermacher S, Rachinger JC, Prell J, Strauss C, Reinsch M, Kunter U, Wienke A, Neumann J, Scheller K (2012) Prophylactic intravenous nimodipine treatment in skull base surgery: pharmacokinetic aspects. Cen Eur Neurosurg 73: 153-159 [abstract]

Weiss M (2012) A model for transit time distributions through organs that accounts for fractal heterogeneity. J Theor Biol 301: 57-61 [abstract]

Weiss M, Li P, Roberts MS (2012) Estimation of sinusoidal flow heterogeneity in normal and diseased rat livers from tracer dilution data using a fractal model. Microcirculation 19: 723-728 [abstract]

Weiss M, Sermsappasuk P, Siegmund W (2012) Modeling the kinetics of digoxin absorption: enhancement by P-glycoprotein inhibition. J Clin Pharmacol 52: 381-387 [abstract]

2011

Gergs U, Kirchhefer U, Buskase J, Kiele-Dunsche K, Buchwalow IB, Jones LR, Schmitz W, Traub O, Neumann J (2011) Sarcoplasmic reticulum Ca2+ release in neonatal rat cardiac myocytes. J Mol Cell Cardiol 51: 682-688 [abstract]

Kang W, Elitzer S, Noh K, Bednarek T, Weiss M (2011) Myocardial pharmacokinetics of ebastine, a substrate for cytochrome P450 2J, in rat isolated heart. Br J Pharmacol 163(8): 1733-1739 [abstract]

Paul M, Meyborg M, Boknik P, Gergs U, Schmitz W, Breithardt G, Wichter T, Neumann J (2011) Autonomic dysfunction in patients with Brugada syndrome: Further biochemical evidence of altered signaling pathways. Pacing Clin Electrophysiol 34(9): 1147-1153 [abstract]

Punkt K, Kusche T, Günther S, Adams V, Jones LR, Neumann J (2011) Changes in metabolic profile and population of skeletal muscle fibers of mice overexpressing calsequestrin: Influence of losartan. Acta Histochem 113: 547-555 [abstract]

Rashan LJ, Franke K, Khine MM, Kelter G, Fiebig HH, Neumann J, Wessjohann LA (2011) Characterization of the anticancer properties of monoglycosidic cardenolides isolated from Nerium oleander and Streptocaulon tomentosum. J Ethnopharmacol 134: 781-788 [abstract]

Schreier B, Rabe S, Schneider B, Ruhs S, Grossmann C, Hauptmann S, Blessing M, Neumann J, Gekle M (2011) Aldosterone/NaCl-induced renal and cardiac fibrosis is modulated by TGF-β responsiveness of T cells. Hypertens Res 34: 623-629 [abstract]

Schubert S, Schwertz H, Weyrich AS, Franks ZG, Lindemann S, Otto M, Behr H, Loppnow H, Schlitt A, Russ M, Presek P, Werdan K, Buerke M (2011) Staphylococcus aureus α-Toxin Triggers the Synthesis of B-Cell Lymphoma 3 by Human Platelets. Toxins 3(2): 120-33 [abstract]

Weiss M (2011) Functional characterization of drug uptake and metabolism in the heart. Expert Opin Drug Metab Toxicol 7(10): 1295-1306 [abstract]

Weiss M, Krejcie TC, Avram MJ (2011) A physiologically based model of hepatic ICG clearance: interplay between sinusoidal uptake and biliary excretion. Eur J Pharm Sci 44(3): 359-365 [abstract]

Weiss M, Reekers M, Vuyk J, Boer F (2011) Circulatory model of vascular and interstitial distribution kinetics of rocuronium: a population analysis in patients. J Pharmacokinet Pharmacodyn 38(2): 165-178 [abstract]

Wijnker PJ, Boknik P, Gergs U, Müller FU, Neumann J, Dos Remedios C, Schmitz W, Sindermann JR, Stienen GJ, van der Velden J, Kirchhefer U (2011) Protein phosphatase 2A affects myofilament contractility in non-failing but not in failing human myocardium. J Muscle Res Cell Motil 32(3): 221-233 [abstract]

 

2010

Boldt A, Gergs U, Pönicke K, Simm A, Silber RE, Neumann J (2010) Inotropic effects of ivabradine in the mammalian heart. Pharmacology 86(5-6): 249-258 [abstract]

Cheng G, Takahashi M, Shunmugavel A, Wallenborn JG, Depaoli-Roach AA, Gergs U, Neumann J, Kuppuswamy D, Menick DR, Cooper G 4th (2010) Basis for MAP4 dephosphorylation-related microtubule network densification in pressure overload cardiac hypertrophy. J Biol Chem 285(49): 38125-38140 [abstract]

Gergs U, Baumann M, Böckler A, Buchwalow I, Ebelt H, Fabritz L, Hauptmann S, Keller N, Kirchhof P, Klöckner U, Pönicke K, Rückschloß U, Schmitz W, Werner F, Neumann J (2010) Cardiac overexpression of the human 5-HT4-receptor in mice. Am J Physiol Heart Circ Physiol 299: H788-H798 [abstract]

Günther S, Baba HA, Hauptmann S, Holzhausen HJ, Großmann C, Punkt K, Kusche T, Jones LR, Gergs U, Neumann J (2010) Losartan reduces mortality in a genetic model of heart failure. Naunyn Schmiedeberg's Arch Pharmacol 382: 265-278 [abstract]

Kirchhefer U, Wehrmeister D, Postma AV, Pohlentz G, Mormann M, Kucerova D, Müller FU, Schmitz W, Schulze-Bahr E, Wilde AA, Neumann J  (2010) The human CASQ2 mutation K206N is associated with hyperglycosylation and altered cellular calcium handling. J Mol Cell Cardiol 49: 95-105 [abstract]

Liu X, Zou Y, Khlentzos AM, Yang Y, Nikolovski J, Weiss M, Roberts MS (2010) Nitric oxide induced sinusoidal relaxation after a propranolol priming dose in the perfused rat liver reduces propranolol availability on subsequent dosing. Clin Exp Pharmacol P 37: 1028-1033 [abstract]

Nass N, Vogel K, Hofmann B, Presek P, Silber RE, Simm A (2010) Glycation of PDGF results in decreased biological activity. Int J Biochem Cell Biol 42: 749-754 [abstract]

Ruf V, Stewart S, Pretorius S, Kubheka M, Lautenschläger C, Presek P, Sliwa K (2010) Medication adherence, self-care behaviour and knowledge on heart failure in urban South Africa: the Heart of Soweto study. Cardiovasc J Afr 21: 86-92 [abstract]

Sziegoleit W, Lautenschläger C, Walther C, Presek P (2010) Hemodynamic effects of eating and prolonged supine position in healthy subjects studied under clinical-pharmacological test conditions. Method Find Exp Clin Pharmacol 32: 585-591 [abstract]

Thilo F, Liu Y, Schulz N, Gergs U, Neumann J, Loddenkemper C, Gollasch M, Tepel M (2010) Increased transient receptor potential vanilloid type 1 (TRPV1) channel expression in hypertrophic heart. Biochem Biophys Res Commun 401: 98-103 [abstract]

Ullrich T, Wesenberg D, Bleuel C, Krauss GJ, Schmid MG, Weiss M, Gübitz G (2010) Chiral separation of the β2-sympathomimetic fenoterol by HPLC and capillary zone electrophoresis for pharmacokinetic studies. Biomed Chromatogr 24: 1125-1129 [abstract]

Weiss M, Li P, Roberts MS (2010) An improved nonlinear model describing the hepatic pharmacokinetics of digoxin: evidence for two functionally different uptake systems and saturable binding. Pharm Res 27: 1999-2007 [abstract]

 

2009

Boknik P, Grote-Wessels S, Barteska G, Jiang M, Müller FU, Schmitz W, Neumann J, Birnbaumer L (2009) Genetic disruption of G proteins, G(i2)alpha or G(o)alpha, does not abolish inotropic and chronotropic effects of stimulating muscarinic cholinoceptors in atrium. Br J Pharmacol 158: 1557-1564 [abstract]

Boldt A, Gergs U, Frenker J, Simm A, Silber RE, Klöckner U, Neumann J (2009) Inotropic effects of L-lysine in the mammalian heart. Naunyn Schmiedeberg's Arch Pharmacol 380: 293-301 [abstract]

Frese T, Bach AG, Mühlbauer E, Pönicke K, Brömme HJ, Welp A, Peschke E (2009) Pineal melatonin synthesis is decreased in type 2 diabetic Goto-Kakizaki rats. Life Sci 85: 526-533 [abstract]

Gergs U, Boknik P, Schmitz W, Simm A, Silber RE, Neumann J (2009) A positive inotropic effect of adenosine in cardiac preparations of right atria from diseased human hearts. Naunyn Schmiedeberg's Arch Pharmacol 379: 533-540 [abstract]

Gergs U, Neumann J, Simm A, Silber RE, Remmers FO, Läer S (2009) Phosphorylation of phospholamban and troponin I through 5-HT4 receptors in the isolated human atrium. Naunyn Schmiedeberg's Arch Pharmacol  379: 349-359 [abstract]

Neumann J (2009) Pain Therapy in Children and Adolescents: Advise Against Metamizole. Dtsch Arztebl Int 106: 55 [abstract]

Sermsappasuk P, Weiss M (2009) Modelling of alpha1-adrenoceptor-mediated temporal dynamics of inotropic response in rat heart to assess ligand binding and signal transduction parameters. Br J Pharmacol 156: 764-773 [abstract]

Weiss M (2009) Cardiac output and systemic transit time dispersion as determinants of circulatory mixing time: a simulation study. J Appl Physiol  107: 445-449 [abstract]

Weiss M, Hassna R, Sermsappasuk P, Bednarek T (2009) Pharmacokinetic-pharmacodynamic modeling of the effect of propofol on alpha1-adrenoceptor-mediated positive inotropy in rat heart. Eur J Pharm Sci 38: 389-94 [abstract]

 

2008

Brüchert N, Mavila N, Boknik P, Baba HA, Fabritz L, Gergs U, Kirchhefer U, Kirchhof P, Matus M, Schmitz W, Depaoli-Roach AA, Neumann J (2008) Inhibitor-2 prevents phosphatase 1 induced cardiac hypertrophy and mortality. Am J Physiol Heart Circ Physiol 295: H1539-H1546 [abstract]

Buchwalow IB, Cacanyiova S, Neumann J, Samoilova VE, Boecker W, Kristek F (2008) The role of arterial smooth muscle in vasorelaxation. Biochem Biophys Res Com 377: 504-507 [abstract]

Gergs U, Boknik P, Schmitz W, Simm A, Silber RE, Neumann J (2008) A positive inotropic effect of ATP in the human cardiac atrium. Am J Physiol Heart Circ Physiol 294: H1716-H1723 [abstract]

Grote-Wessels S, Baba HA, Boknik P, El-Armouche A, Fabritz L, Gillmann HJ, Kucerova D, Matus M, Müller FU, Neumann J, Schmitz M, Stümpel F, Theilmeier G, Wohlschlaeger J, Schmitz W, Kirchhefer U (2008) Inhibition of protein phosphatase 1 by inhibitor-2 exacerbates progression of cardiac failure in a model with pressure overload. Cardiovasc Res 79: 464-471 [abstract]

Levkau B, Schäfers M, Wohlschlaeger J, von Wnuck Lipinski K, Keul P, Hermann S, Kawaguchi N, Kirchhof P, Fabritz L, Stypmann J, Stegger L, Flögel U, Schrader J, Fischer J, Hsieh P, Ou YL, Mehrhof F, Tiemann K, Ghanem A, Matus M, Neumann J, Heusch G, Schmid KW, Conway EM, Baba HA (2008) Survivin determines cardiac function by controlling total cardiomyocyte number. Circulation  117: 1583-1593 [abstract]

Neumann J (2008) New pathophysiological function of protein phosphatase 2A? Cardiovasc Res 80(1): 7-8 [abstract]

Peschke E, Wolgast S, Bazwinsky I, Pönicke K, Muhlbauer E (2008) Increased melatonin synthesis in pineal glands of rats in streptozotocin induced type 1 diabetes. J Pineal Res 45: 439-448 [abstract]

Sermsappasuk P, Abdelrahman O, Weiss M (2008) Cardiac pharmacokinetics and inotropic response of verapamil in rats with endotoxemia. J Pharm Sci 97: 2798-2804 [abstract]

Sermsappasuk P, Hrynyk R, Gubernator J, Weiss M (2008) Reduced uptake of liposomal idarubicin in the perfused rat heart. Anti-Cancer Drug 19: 729-32 [abstract]

Wang J, Weiss M, D'Argenio David Z (2008) A note on population analysis of dissolution-absorption models using the inverse Gaussian function. J Clin Pharmacol 48: 719-725 [abstract]

Weiss M (2008) How does obesity affect residence time dispersion and the shape of drug disposition curves? Thiopental as an example. J Pharmakokinet Phar 35: 325-336 [abstract]

Weiss M, Hung DY, Poenicke K, Roberts MS (2008) Kinetic analysis of saturable hepatic uptake of digoxin and its inhibition by rifampicin. Eur J Pharm Sci 34: 345-350 [abstract]

 

2007

Gergs U, Berndt T, Buskase J, Jones LR, Kirchhefer U, Müller FU, Schluter KD, Schmitz W, Neumann J (2007) On the role of junctin in cardiac Ca2+ handling, contractility, and heart failure. Am J Physiol Heart Circ Physiol 293(1): 728-734 [abstract]

Gergs U, Pönicke K, Neumann J (2007) Therapie der koronaren Herzkrankheit durch bradykardisierende Substanzen: am Beispiel des Ivabradins. Ärzteblatt Sachsen-Anhalt 12: 18-21

Härtel FV, Rodewald CW, Aslam M, Gündüz D, Hafer L, Neumann J, Piper HM, Noll T (2007) Extracellular ATP induces assembly and activation of the myosin light chain phosphatase complex in endothelial cells. Cardiovasc Res 74(3): 487-496 [abstract]

Kirchhefer U, Klimas J, Baba HA, Buchwalow IB, Fabritz L, Huls M, Matus M, Muller FU, Schmitz W, Neumann J (2007) Triadin is a critical determinant of cellular Ca cycling and contractility in the heart. Am J Physiol Heart Circ Physiol 293(5): H3165-3174 [abstract]

Kirchhof P, Klimas J, Fabritz L, Zwiener M, Jones LR, Schäfers M, Hermann S, Boknik P, Schmitz W, Breithardt G, Kirchhefer U, Neumann J (2007) Stress and high heart rate provoke ventricular tachycardia in mice expressing triadin. J Mol Cell Cardiol 42(5): 962-971 [abstract]

Lansky P, Sanda P, Weiss M (2007) Modeling the influence of non-adherence on antibiotic efficacy: application to ciprofloxacin. Int J Clin Pharm Th 45(8): 438-447 [abstract]

Pang KS, Weiss M, Macheras P (2007) Advanced pharmacokinetic models based on organ clearance, circulatory, and fractal concepts. AAPS J 9(2): E268-E283 [abstract]

Sermsappasuk P, Abdelrahman O, Weiss M (2007) Modeling Cardiac Uptake and Negative Inotropic Response of Verapamil in Rat Heart: Effect of Amiodarone. Pharm Res 24(1): 48-57 [abstract]

Sziegoleit W, Dannenberg K, Konschak A, Lautenschläger C, Presek P (2007) Influence of systemically given placebo, trapidil and isosorbide dinitrate on norepinephrine-evoked hand vein constriction in healthy subjects. Arzneimittel-Forsch 57(2): 81-86 [abstract]

Sziegoleit W, Dannenberg K, Presek P, Thomas E (2007) Effect of locally applied trapidil on norepinephrine- and dinoprost-evoked hand vein constriction in healthy men. Int J Clin Pharm Th 45(1): 10-15 [abstract]

Weiss M (2007) Mechanistic modeling of digoxin distribution kinetics incorporating slow tissue binding. Eur J Pharm Sci 30(3-4): 256-263 [abstract]

Weiss M (2007) Residence time dispersion as a general measure of drug distribution kinetics: estimation and physiological interpretation. Pharm Res 24(11): 2025-2030 [abstract]

Weiss M, Krejcie TC, Avram MJ (2007) A minimal physiological model of thiopental distribution kinetics based on a multiple indicator approach. Drug Metab Dispos 35(9): 1525-1532 [abstract]

Weiss M, Krejcie TC, Avram MJ (2007) Circulatory transport and capillary-tissue exchange as determinants of the distribution kinetics of inulin and antipyrine in dog. J Pharm Sci 96(4): 913-926 [abstract]

 

2006

Fischer H, Fischer J, Boknik P, Gergs U, Schmitz W, Domschke W, Konturek JW, Neumann J (2006) Reduced expression of Ca(2+)-regulating proteins in the upper gastrointestinal tract of patients with achalasia. World J Gastroentero 12(37): 6002-6007 [abstract]

Kirchhefer U, Hanske G, Jones LR, Justus I, Kaestner L, Lipp P, Schmitz W, Neumann J (2006) Overexpression of junctin causes adaptive changes in cardiac myocyte Ca(2+) signaling. Cell Calcium 39(2): 131-142 [abstract]

Knapp J, Aleth S, Balzer F, Gergs U, Schmitz W, Neumann J (2006) Comparison of contractile responses in isolated mouse aorta and pulmonary artery: Influence of strain and sex. J Cardiovasc Pharm 48(1): 820-826 [abstract]

Neumann J (2006) The cardiac beta-adrenoceptors: Where and why? Cardiovasc Res 71(1): 6-7 [abstract]

Pönicke K, Gröner F, Heinroth-Hoffmann I, Brodde OE (2006) Agonist-specific activation of the beta(2)-adrenoceptor/G(s)-protein and beta(2)-adrenoceptor/G(i)-protein pathway in adult rat ventricular cardiomyocytes. Br J Pharmacol 147(7): 714-719 [abstract]

Sermsappasuk P, Baek M, Weiss M (2006) Kinetic analysis of myocardial uptake and negative inotropic effect of amiodarone in rat heart. Eur J Pharm Sci 28(3): 243-248 [abstract]

Weber T, Neumann J, Meissner A, Grosse Hartlage M, Van Aken H, Hanske G, Schmitz W, Boknik P (2006) Reduced serine-16 and threonine-17 phospholamban phosphorylation in stunning of conscious dogs: No evidence for any involvement of protein kinase A or protein phosphatases. Basic Res Cardiol 101: 253-260 [abstract]

Weiss M, Giessler C, Kang W (2006) Effects of idarubicin and idarubicinol on rat coronary resistance and vasoconstrictor responsiveness of isolated aorta and mesentery. Anti-Cancer Drug 17(1): 69-74 [abstract]

Weiss M, Krejcie TC, Avram MJ (2006) Transit time dispersion in pulmonary and systemic circulation: effects of cardiac output and solute diffusivity. Am J Physiol Heart Circ Physiol 291(2): H861-H870 [abstract]

 

2005

Baek M, Weiss M (2005) Mechanism-based modeling of reduced inotropic responsiveness to digoxin in endotoxemic rat hearts. Eur J Pharmacol 514(1): 43-51 [abstract]

Baek M, Weiss M (2005) Down-regulation of Na+ pump alpha 2 isoform in isoprenaline-induced cardiac hypertrophy in rat: evidence for increased receptor binding affinity but reduced inotropic potency of digoxin. J Pharmacol Exp Ther 313(2): 731-739 [abstract]

Buchwalow IB, Minin EA, Samoilova VE, Boecker W, Wellner M, Schmitz W, Neumann J, Punkt K (2005) Compartmentalization of NO signaling cascade in skeletal muscles. Biochem Biophys Res Commun 330(2): 615-621 [abstract]

Fälker K, Lange D, Presek P (2005) P2Y12 ADP receptor-dependent tyrosine phosphorylation of proteins of 27 and 31 kDa in thrombin-stimulated human platelets. Thromb Haemost 93(5): 880-888 [abstract]

Kirchhefer U, Baba HA, Bokník P, Breeden KM, Mavila N, Brüchert N, Justus I, Matus M, Schmitz W, Depaoli-Roach AA, Neumann J (2005) Enhanced cardiac function in mice overexpressing protein phosphatase Inhibitor-2. Cardiovasc Res 68(1): 98-108 [abstract]

Kornhuber ME, Presek P, Zierz S (2005) [Differential influence of immune therapy on relapses and progression in multiple sclerosis: interpretation and therapeutic consequences]. 
Fortschr Neurol Psychiatr 73(3): 143-149 [abstract]

Minin EA, Buchwalow IB, Wellner M, Palmes D, Spiegel HU, Neumann J, Boecker W, Herbst H (2005) L-Arginine-NO-cGMP signaling following acute liver injury in the rat. Exp Toxicol Pathol 57: 161-171 [abstract]

Müller FU, Lewin G, Baba HA, Bokník P, Fabritz L, Kirchhefer U, Kirchhof P, Loser K, Matus M, Neumann J, Riemann B, Schmitz W (2005) Heart-directed expression of a human cardiac isoform of cAMP-response element modulator in transgenic mice. J Biol Chem 280(8): 6906-6914 [abstract]

Vahlhaus C, Neumann J, Lüss H, Wenzelburger F, Tjan TD, Hammel D, Scheld HH, Schmitz W, Breithardt G, Wichter T (2005) Ischemic preconditioning by unstable angina reduces the release of CK-MB following CABG and stimulates left ventricular HSP-72 protein expression. J Card Surg 20(5): 412-419 [abstract]

Voigt W, Kegel T, Weiss M, Mueller T, Simon H, Schmoll HJ (2005) Potential activity of paclitaxel, vinorelbine and gemcitabine in anaplastic thyroid carcinoma. J Cancer Res Clin Oncol 131(9): 585-590 [abstract]

 

 

Kontakt

Direktor:
Prof. Dr. med. Joachim Neumann

Sekretariat:
Frau Stephanie Simmrodt

Telefon:
(0345) 557 1686

Telefax: 
(0345) 557 1835

E-Mail:
Öffnet ein Fenster zum Versenden der E-Mailsekr.pharmatox(at)medizin.uni-halle.de

Besucheradresse:
Magdeburger Straße 4
06112 Halle (Saale)