Forschung/ Publikationen/ Arbeitsgruppen
Aktuelle Publikationen aus dem Anatomischen Institut im Überblick
2013
Beutel G, Perthel R, Suntharalingam M, Bode-Böger SM, Martens-Lobenhoffer J, Kielstein JT, Kielstein H. (2013) Effect of chronic elevated asymmetric dimethylarginine (ADMA) levels on granulopoiesis. Ann Hematol. 92(4):505-8.
Jäger K, Wolf S, Dobrowolny H, Steiner J, Nave H, Maronde E, Bogerts B, Bernstein HG. (2013) Differential topochemistry of three cationic amino acid transporter proteins, hCAT1, hCAT2 and hCAT3, in the adult human brain. Amino Acids. 44(2):423-33.
Mühlbauer E, Bazwinsky-Wutschke I, Wolgast S, Labucay K, Peschke E. (2013) Differential and day-time dependent expression of nuclear receptors RORα, RORβ, RORγ and RXRα in the rodent pancreas and islet. Mol Cell Endocrinol. 365(2):129-38.
Nugraha B, Korallus C, Kielstein H, Gutenbrunner C. (2013) CD3+CD56+ Natural Killer T cells in fibromyalgia syndrome patients: relation to anxiety and depression. Clin Exp Rheumatol [Epub ahead of print]
2012
Bähr I, Bazwinsky-Wutschke I, Wolgast S, Hofmann K, Streck S, Mühlbauer E, Wedekind D, Peschke E. (2012) GLUT4 in the endocrine pancreas--indicating an impact in pancreatic islet cell physiology? Horm Metab Res. 44(6):442-50.
Bähr I, Mühlbauer E, Albrecht E, Peschke E (2012) Evidence of the receptor-mediated influence of melatonin on pancreatic glucagon secretion via the G?q protein-coupled and PI3K signaling pathways. J PINEAL RES, 53: 390-8.
Bazwinsky-Wutschke I, Wolgast S, Mühlbauer E, Albrecht E, Peschke E. (2012) Phosphorylation of cyclic AMP-response element-binding protein (CREB) is influenced by melatonin treatment in pancreatic rat insulinoma β-cells (INS-1). J Pineal Res. 53(4):344-57.
Biemann R, Navarrete Santos An, Navarrete Santos Al, Riemann D, Knelangen J, Blüher M, Fischer B. (2012) Endocrine disrupting chemicals affect the adipogenic differentiation of mesenchymal stem cells in distinct ontogenetic windows. Biochem Biophys Res Commun. 417:747-52.
Ebrahimi F, Koch M, Pieroh P, Ghadban C, Hobusch C, Bechmann I, Dehghani F. (2012) Time dependent neuroprotection of mycophenolate mofetil: effects on temporal dynamics in glial proliferation, apoptosis, and scar formation. J Neuroinflammation. 9:89.
Fowler PA, Bellingham M, Sinclair KD, Evans NP, Pocar P, Fischer B, Schaedlich K, Schmidt JS, Amezaga MR, Bhattacharya S, Rhind SM, O'Shaughnessy PJ. (2012) Impact of endocrine-disrupting compounds (EDCs) on female reproductive health. Mol Cell Endocrinol. 355:231-239.
Grabiec U, Koch M, Kallendrusch S, Kraft R, Hill K, Merkwitz C, Ghadban C, Lutz B, Straiker A, Dehghani F. (2012) The endocannabinoid N-arachidonoyldopamine (NADA) exerts neuroprotective effects after excitotoxic neuronal damage via cannabinoid receptor 1 (CB(1)). Neuropharmacology. 62(4):1797-807.
Hezel M, Ebrahimi F, Koch M, Dehghani F. (2012) Propidium iodide staining: a new application in fluorescence microscopy for analysis of cytoarchitecture in adult and developing rodent brain. Micron. 43(10):1031-8.
Jungebluth P, Bader A, Baiguera S, Möller S, Jaus M, Lim ML, Fried K, Kjartansdóttir KR, Go T, Nave H, Harringer W, Lundin V, Teixeira AI, Macchiarini P. (2012) The concept of in vivo airway tissue engineering. Biomaterials. 33:4319-4326.
Kallendrusch S, Hobusch C, Ehrlich A, Nowicki M, Ziebell S, Bechmann I, Geisslinger G, Koch M, Dehghani F. (2012) Intrinsic Up-Regulation of 2-AG Favors an Area Specific Neuronal Survival in Different In Vitro Models of Neuronal Damage. PLoS One. 7(12):e51208.
Kallendrusch S, Hobusch C, Ehrlich A, Ziebell S, Ueda N, Geisslinger G, Koch M, Dehghani F. (2012) Site-specific and time-dependent activation of the endocannabinoid system after transection of long-range projections. PLoS One. 7(3):e33537.
Kielstein JT, Suntharalingam M, Perthel R, Rong S, Martens-Lobenhoffer J, Jäger K, Bode-Böger SM, Nave H. (2012) Asymmetric dimethylarginine may mediate increased heat pain threshold in experimental chronic kidney disease. Nephrol Dial Transplant. 27:899-902.
Knelangen JM, Kurz R, Schagdarsurengin U, Fischer B, Navarrete Santos A. (2012) Short-time glucose exposure of embryonic carcinoma cells impairs their function as terminally differentiated cardiomyocytes. Biochem Biophys Res Commun. 420:230-235.
Königsdorf CAI, Navarrete Santos A, Schmidt JS, Fischer S, Fischer B. (2012) Expression profile of fatty acid metabolism genes in preimplantation blastocysts of obese and non-obese mice. Obesity Facts. 5:575–586.
Llobat L, Marco-Jiménez F, Peñaranda DS, Thieme R, Navarrete Santos A, Vicente JS. (2012) mRNA expression in rabbit blastocyst and endometrial tissue of candidate gene involved in gestational losses. Reprod Dom Anim. 47:281-287.
Mühlbauer E, Albrecht E, Bazwinsky-Wutschke I, Peschke E. (2012) Melatonin influences insulin secretion primarily via MT(1) receptors in rat insulinoma cells (INS-1) and mouse pancreatic islets. J Pineal Res. 52(4):446-59.
Pocar P, Fiandanese N, Secchi C, Berrini A, Fischer B, Schmidt JS, Schaedlich K, Borromeo V. (2012) Exposure to di(2-ethyl-hexyl) phthalate (DEHP) in utero and during lactation causes long-term pituitary-gonadal axis disruption in mouse male and female offspring. Endocrinology. 153:937-48.
Pocar P, Fiandanese N, Secchi C, Berrini A, Fischer B, Schmidt JS, Schaedlich K, Rhind SM, Zhang Z, Borromeo V. (2012) Effects of polychlorinated biphenyls in CD-1 mice: reproductive toxicity and intergenerational transmission. Toxicol Sci. 126:213-226.
Schmidt JS, Schaedlich K, Fiandanese N, Pocar P, Fischer B. (2012) Effects of Di(2-ethylhexyl) Phthalate (DEHP) on Female Fertility and Adipogenesis in C3H/N mice. Environmental Health Perspectives. 120:1123-9.
Schroeder IS, Sulzbacher S, Nolden T, Fuchs J, Czarnota J, Meisterfeld R, Himmelbauer H, Wobus AM (2012) Induction and selection of sox17-expressing endoderm cells generated from murine embryonic stem cells. CELLS TISSUES ORGANS, 195: 507-23.
Thieme R, Ramin N, Fischer S, Püschel B, Fischer B, Navarrete Santos A. (2012) Gastrulation in rabbit blastocysts depends on insulin and the insulin-like-growth-factor 1. Mol Cell Endocrinol. 348:112-119.
Thieme R, Schindler M, Ramin N, Fischer S, Mühleck B, Fischer B, Navarrete Santos A. (2012) Insulin growth factor adjustment in preimplantation rabbit blastocysts and uterine tissues in response to maternal type 1 diabetes. Mol Cell Endocrinol. 358:96-103.
Wrann CD, Eguchi J, Bozec A, Xu Z, Mikkelsen T, Gimble J, Nave H, Wagner EF, Ong SE, Rosen ED. (2012) FOSL2 promotes leptin gene expression in human and mouse adipocytes. J Clin Invest. 122:1010-1021.
Wrann CD, Laue T, Hübner L, Kuhlmann S, Jacobs R, Goudeva L, Nave H. (2012) Short-term and long-term leptin exposure differentially affetcs human natural killer cell immune functions. Am J Physiol Endocrinol Metab. 302:E108-116.
2011
Bazwinsky-Wutschke I, Paulsen F, Stövesandt D, Holzhausen HJ, Heine HJ, Peschke E. (2011) Anatomical changes after pneumonectomy. Ann Anat. 193(2):168-72.
Horling K, Navarrete Santos A, Fischer B. (2011) The AhR is constitutively activated and affects granulosa cell features in the human cell line KGN. Mol Hum Reprod. 17:104-114.
Jäger K, Nielitz A, Garreis F, Sel S, Nave H, Paulsen FP. (2011) In vitro evidence of involvement of the epithelial y+ transporter in β-defensin production on the ocular surface. Ann Anat. 193:479-485.
Knelangen J, van der Hoek M, Kong WC, Owens J, Fischer B, Navarrete Santos A. (2011) MicroRNA expression profile during adipogenic differentiation in mouse embryonic stem cells. Physiol Genomics. 43:611-620.
Koch M, Kreutz S, Böttger C, Benz A, Maronde E, Ghadban C, Korf HW, Dehghani F. (2011) Palmitoylethanolamide protects dentate gyrus granule cells via peroxisome proliferator-activated receptor-α. Neurotox Res. 19(2):330-40.
Koch M, Kreutz S, Böttger C, Grabiec U, Ghadban C, Korf HW, Dehghani F. (2011) The cannabinoid WIN 55,212-2-mediated protection of dentate gyrus granule cells is driven by CB1 receptors and modulated by TRPA1 and Cav 2.2 channels. Hippocampus. 21(5):554-64.
Lautenbach A, Breitmeier D, Kuhlmann S, Nave H. (2011) Human obesity reduces the number of hepatic leptin receptor (ob-R) expressing NK cells. Endocr Res. 36:158-166.
Maronde E, Saade A, Ackermann K, Goubran-Botros H, Pagan C, Bux R, Bourgeron T, Dehghani F, Stehle JH. (2011) Dynamics in enzymatic protein complexes offer a novel principle for the regulation of melatonin synthesis in the human pineal gland. J Pineal Res. 5(1):145-55.
Mühlbauer E, Albrecht E, Hofmann K, Bazwinsky-Wutschke I, Peschke E. (2011) Melatonin inhibits insulin secretion in rat insulinoma β-cells (INS-1) heterologously expressing the human melatonin receptor isoform MT2. J Pineal Res. 51(3):361-72.
Nave H, Beutel G, Kielstein JT. (2011) Obesity-related immunodeficiency as a major risk factor in patients with pandemic influenza A (H1N1) virus infection. Lancet Infect Dis. 11:14-15.
Stadler J, Le TP, Haas P, Nave H. (2011) Distinct effects of NPY13-36, a specific NPY Y2 agonist, in a model of rodent endotoxemia on leukocyte subsets and cytokine levels. Ann Anat. 193:486-493.
Stephan M, Radicke A, Leutloff S, Schmiedl A, Pabst R, von Hörsten S, Dettmer S, Lotz J, Nave H. (2011) Dipeptidyl peptidase IV (DPP4)-deficiency attenuates diet-induced obesity in rats: possible implications for the hypothalamic neuropeptidergic system. Behav Brain Res. 216:712-718.
2010
Bazwinsky-Wutschke I, Wolgast S, Mühlbauer E, Peschke E. (2010) Distribution patterns of calcium-binding proteins in pancreatic tissue of non-diabetic as well as type 2 diabetic rats and in rat insulinoma beta-cells (INS-1). Histochem Cell Biol. 134(2):115-27.
Behrendt P, Buchenauer T, Horn R, Brabant G, Jacobs R, Bode F, Stephan M, Nave H. (2010) Diet-induced obesity and exogenous leptin affect tissue leukocyte distribution and serum levels of cytokines in F344 rats. Endocrine. 38:104-112.
Benz AH, Shajari M, Peruzki N, Dehghani F, Maronde E. (2010) Early growth response-1 induction by fibroblast growth factor-1 via increase of mitogen-activated protein kinase and inhibition of protein kinase B in hippocampal neurons. Br J Pharmacol. 160(7):1621-30.
Bishay P, Schmidt H, Marian C, Häussler A, Wijnvoord N, Ziebell S, Metzner J, Koch M, Myrczek T, Bechmann I, Kuner R, Costigan M, Dehghani F, Geisslinger G, Tegeder I. (2010) R-flurbiprofen reduces neuropathic pain in rodents by restoring endogenous cannabinoids. PLoS One. 5(5):e10628.
Dehghani F, Sayan M, Conrad A, Evers J, Ghadban C, Blaheta R, Korf HW, Hailer NP. (2010) Inhibition of microglial and astrocytic inflammatory responses by the immunosuppressant mycophenolate mofetil. Neuropathol Appl Neurobiol. 36(7):598-611.
Ebrahimi F, Hezel M, Koch M, Ghadban C, Korf HW, Dehghani F. (2010) Analyses of neuronal damage in excitotoxically lesioned organotypic hippocampal slice cultures. Ann Anat. 192(4):199-204.
Fischer S, Navarrete Santos A, Thieme R, Ramin N, Fischer B. (2010) Adiponectin stimulates glucose uptake in rabbit blastocysts. Biol Reprod. 83:859-865.
Jilg A, Lesny S, Peruzki N, Schwegler H, Selbach O, Dehghani F, Stehle JH. (2010) Temporal dynamics of mouse hippocampal clock gene expression support memory processing. Hippocampus. 20(3):377-88.
Held N, Smits BMJ, Gockeln R, Schubert S, Nave H, Cuppen E, Hedrich H-J, Wedekind D. (2010) A Mutation in Myo15 Leads to Usher-Like Symptoms in LEW-ci2 rats. PLoS ONE. 6:e15669.
Merz F, Müller M, Taucher-Scholz G, Rödel F, Stöcker H, Schopow K, Laprell L, Dehghani F, Durante M, Bechmann I. (2010) Tissue slice cultures from humans or rodents: a new tool to evaluate biological effects of heavy ions. Radiat Environ Biophys. 49(3):457-62.
Pukrop T, Dehghani F, Chuang HN, Lohaus R, Bayanga K, Heermann S, Regen T, Van Rossum D, Klemm F, Schulz M, Siam L, Hoffmann A, Trümper L, Stadelmann C, Bechmann I, Hanisch UK, Binder C. (2010) Microglia promote colonization of brain tissue by breast cancer cells in a Wnt-dependent way. Glia. 58(12):1477-89.
Ramin N, Thieme R, Fischer S, Schindler M, Schmidt T, Fischer B, Navarrete Santos A. (2010) Maternal diabetes impairs gastrulation and insulin and IGF1 receptor expression in rabbit blastocysts. Endocrinology. 151:4158-4167.
Schaedlich K, Knelangen J, Navarrete Santos A, Fischer B, Navarrete Santos A. (2010) A simple method to sort ESC-derived adipocytes. Cytometry: Part A. 77A:990-995.
Wrann CD, Ehmer U, Lautenbach A, Kuhlmann S, Nave H. (2010) Obesity and NK cells affect the expression of the long-form of the leptin receptor Ob-Rb in the liver of F344 rats. Exp Toxicol Pathol. 62:1-8.
