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Chary Nimmagadda, Master of Biotech.

Project: "Identification and Characterization of a Novel PKD Substrates"

Members of Protein kinase D family (PKC µ /PKD, PKD2 and PKC υ /PKD3), a subfamily of Calcium/ Calmodulin dependent kinase (CAMK) super family are serine/ threonine kinases, occupying an important position in the signal transduction pathways downstream of diacylglycerol (DAG) and Protein kinase C (PKC). The three PKD isoforms share striking similarities and have been implicated in regulation of multiple biological processes including cell survival, proliferation, apoptosis, angiogenesis and motility. Important role of PKD’s in each of these physiological and pathological processes further underscores the significance of identifying and characterizing novel PKD substrates, thus providing a better insight into PKD’s role in signaling and regulation of cellular processes.


Supervisor: Prof. Seufferlein


  • since 2008: PhD student in the lab of Thomas Seufferlein
  • 2007 - 2008: Research assistant in the lab of Prof S. Mahalingam (Center for DNA Finger Printing and Diagnostics, India)
  • 2006: Masters in Biotechnology at Bharathidasan University, India. 
    (Masters thesis title: Effect of anti-dementia drugs on DNA polymerase β activity (BER pathway) under Prof: Kalluri Subba Rao, University of Hyderabad, India) 

 

contact:
Phone: +49-(0)345-557 2253
charynsbt(at)gmail.com