Publications (last years)

  • Längrich T, Bork K, Horstkorte R, Weber V, Hofmann B, Fuszard M, Olzscha H (2022):
     Disturbance of Key Cellular Subproteomes upon Propofol Treatment Is Associated with Increased Permeability of the Blood-Brain Barrier.
    Proteomes. 10(3):28
  • Selke P, Bork K, Zhang T, Wuhrer M, Strauss C, Horstkorte R, Scheer M (2021):
     Glycation Interferes with the Expression of Sialyltransferases in Meningiomas.
    Cells. 10(12):3298
  • Wedekind H, Kats E, Weiss AC, Thiesler H, Klaus C, Kispert A, Horstkorte R, Neumann H, Weinhold B, Münster-Kühnel A, Abeln M (2021):
     Uridine diphosphate-N-acetylglucosamine-2-epimerase/N-acetylmannosamine kinase deletion in mice leads to lethal intracerebral hemorrhage during embryonic development.
    Glycobiology. 31(11):1478-1489
  • Franzka P, Henze H, Jung MJ, Schüler SC, Mittag S, Biskup K, Liebmann L, Kentache T, Morales J, Martínez B, Katona I, Herrmann T, Huebner AK, Hennings JC, Groth S, Gresing L, Horstkorte R, Marquardt T, Weis J, Kaether C, Mutchinick OM, Ori A, Huber O, Blanchard V, von Maltzahn J, Hübner CA(2021):
     GMPPA defects cause a neuromuscular disorder with α-dystroglycan hyperglycosylation.
    J Clin Invest. 131(9):e139076
  • Rosenstock P, Kaufmann T (2021):
     Sialic Acids and Their Influence on Human NK Cell Function.
    Cells. 10(2):263
  • Selke P, Rosenstock P, Bork K, Strauss C, Horstkorte R, Scheer M (2000):
     Glycation of benign meningioma cells leads to increased invasion.
    Biol Chem. 402(7):849-859
  • Weber V, Olzscha H, Längrich T, Hartmann C, Jung M, Hofmann B, Horstkorte R, Bork K (2020):
     Glycation Increases the Risk of Microbial Traversal through an Endothelial Model of the Human Blood-Brain Barrier after Use of Anesthetics.
    J Clin Med. 9(11):3672
  • Rosenstock P, Bork K, Massa C, Selke P, Seliger B, Horstkorte R (2020):
     Sialylation of Human Natural Killer (NK) Cells is Regulated by IL-2.
    J Clin Med. 9(6):1816
  • Nagasundaram M, Horstkorte R, Gnanapragassam VS (2020):
     Sialic Acid Metabolic Engineering of Breast Cancer Cells Interferes with Adhesion and Migration.
    Molecules. 25(11):2632
  • Scheer M, Bork K, Simon F, Nagasundaram M, Horstkorte R, Gnanapragassam VS (2020):
     Glycation Leads to Increased Polysialylation and Promotes the Metastatic Potential of Neuroblastoma Cells.
    Cells. 9(4):868
  • Weber V, Bork K, Horstkorte R, Olzscha H (2020):
     Analyzing the Permeability of the Blood-Brain Barrier by Microbial Traversal through Microvascular Endothelial Cells.
    J Vis Exp. (156)
  • Klaus C, Hansen JN, Ginolhac A, Gérard D, Gnanapragassam VS, Horstkorte R, Rossdam C, Buettner FFR, Sauter T, Sinkkonen L, Neumann H, Linnartz-Gerlach B (2020):
     Reduced sialylation triggers homeostatic synapse and neuronal loss in middle-aged mice.
    Neurobiol Aging. 88:91-107
  • Simon F, Bork K, Gnanapragassam VS, Baldensperger T, Glomb MA, Di Sanzo S, Ori A, Horstkorte R (2019):
     Increased Expression of Immature Mannose-Containing Glycoproteins and Sialic Acid in Aged Mouse Brains.
    Int J Mol Sci. 20(24):6118
  • Ye Z, Mittag S, Schmidt M, Simm A, Horstkorte R, Huber O (2019):
     Wnt Glycation Inhibits Canonical Signaling.
    Cells. 8(11):1320
  • Bezold V, Rosenstock P, Scheffler J, Geyer H, Horstkorte R, Bork K (2019):
     Glycation of macrophages induces expression of pro-inflammatory cytokines and reduces phagocytic efficiency.
    Aging (Albany NY). 11(14):5258-5275
  • Pogoryelova O, Urtizberea JA, Argov Z, Nishino I, Lochmüller H; ENMC workshop study group (2019):
     237th ENMC International Workshop: GNE myopathy - current and future research Hoofddorp, The Netherlands, 14-16 September 2018.
    Neuromuscul Disord. 29(5):401-410
  • Rosenstock P, Bezold V, Bork K, Scheffler J, Horstkorte R (2019):
     Glycation interferes with natural killer cell function.
    Mech Ageing Dev. 178:64-71
  • Scheffler J, Bork K, Bezold V, Rosenstock P, Gnanapragassam VS, Horstkorte R (2018):
     Ascorbic acid leads to glycation and interferes with neurite outgrowth.
    Exp Gerontol. 117:25-30
  • Frank F, Bezold V, Bork K, Rosenstock P, Scheffler J, Horstkorte R (2019):
     Advanced glycation endproducts and polysialylation affect the turnover of the neural cell adhesion molecule (NCAM) and the receptor for advanced glycation endproducts (RAGE).
    Biol Chem. 400(2):219-226
  • Volkers G, Lizak C, Niesser J, Rosell FI, Preidl J, Gnanapragassam VS, Horstkorte R, Rademann J, Strynadka NCJ (2018):
     Structural Basis for Binding of Fluorescent CMP-Neu5Ac Mimetics to Enzymes of the Human ST8Sia Family.
    ACS Chem Biol. 13(8):2320-2328
  • Wratil PR, Horstkorte R (2017):
     Metabolic Glycoengineering of Sialic Acid Using N-acyl-modified Mannosamines.
    J Vis Exp. (129):55746
  • Rosenstock P, Horstkorte R, Gnanapragassam VS, Harth J, Kielstein H (2017):
     Siglec-7 expression is reduced on a natural killer (NK) cell subset of obese humans.
    Immunol Res. 65(5):1017-1024
  • Navarrete Santos A, Jacobs K, Simm A, Glaubitz N, Horstkorte R, Hofmann B (2017):
     Dicarbonyls induce senescence of human vascular endothelial cells.
    Mech Ageing Dev. 166:24-32
  • Bork K, Weidemann W, Berneck B, Kuchta M, Bennmann D, Thate A, Huber O, Gnanapragassam VS, Horstkorte R (2017):
     The expression of sialyltransferases is regulated by the bioavailability and biosynthesis of sialic acids.
    Gene Expr Patterns. 23-24:52-58
  • Goschzik T, Cremer H, Gnanapragassam VS, Horstkorte R, Bork K, Diestel S (2017):
     Mutation of a putative MAP kinase consensus site regulates NCAM endocytosis and NCAM-dependent neurite outgrowth.
    Neurosci Res. 120:28-35
  • Kreuzmann D, Horstkorte R, Kohla G, Kannicht C, Bennmann D, Thate A, Bork K (2017):
     Increased Polysialylation of the Neural Cell Adhesion Molecule in a Transgenic Mouse Model of Sialuria.
    Chembiochem. 18(13):1188-1193