PD Dr. rer. nat. Bayram Edemir

Suche

Herr Edemir ist der Wissenschaftliche Koordinator der Universitätsklinik und Poliklinik für Innere Medizin IV und des Forschungslabores von Frau Professor Dierks. In seiner Funktion betreut und koordiniert er unter anderem die wissenschaftlichen Projekte unserer Einrichtung. Des Weiteren leitet und koordiniert Dr. Edemir den Aufbau der molekularen Diagnostik Plattform.

  • Regulation der Genexpression bei der Tumorentstehung
  • Identifikation von neuen Zielgenen als neue Therapieoptionen
  • Mechanismen der Zellmigration und die Rolle der Aquaporine dabei
  • Identifikation von Biomarkern für eine verbesserte Diagnostik
  • seit 2014 Wissenschaftlicher Koordinator an der Universitätsklinik und Poliklinik für Innere Medizin IV 
  • 2012 Habilitation an der Medizinischen Fakultät der WWU-Münster. Venia Legendi für das Fach Experimentelle und Molekulare Nephrologie 
  • 2012 International Early Career Physiologist Award, verliehen durch The American Physiological Society
  • 2003 Promotion am Fachbereich Biologie, Freie Universität Berlin und am Forschungsinstitut für Molekulare Pharmakologie
  • 1999 Diplom in Biologie, FU-Berlin
  • Deutsche Forschungsgemeinschaft (DFG)
  • Else-Kröner-Fresenius Stiftung
  • Innovative Medizinische Forschung, WWU-Münster 

2020

Ciarimboli G., Theil G., Bialek J., Edemir B.: (2020) Contribution and Expression of Organic Cation Transporters and Aquaporin Water Channels in Renal Cancer. Reviews of Physiology Biochemistry and Pharmacology, 48: 1-10 32772272

Edemir B.: (2020) Identification of Prognostic Organic Cation and Anion Transporters in Different Cancer Entities by In Silico Analysis. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 21: 1-10 32599841

Groß A., Chernyakov D., Gallwitz L., Bornkessel N., Edemir B.: (2020) Deletion of Von Hippel-Lindau Interferes with Hyper Osmolality Induced Gene Expression and Induces an Unfavorable Gene Expression Pattern. Cancers, 12: 2-12 32059438

Kaiser M., Edemir B.: (2020) Lithium Chloride and GSK3 Inhibition Reduce Aquaporin-2 Expression in Primary Cultured Inner Medullary Collecting Duct Cells Due to Independent Mechanisms. Cells, 9: 1-10 32340354

Pauli C., Liu Y., Rohde C., Cui C., Fijalkowska D., Gerloff D., Walter C., Krijgsveld J., Dugas M., Edemir B., Pabst C., Mueller L.P., Zhou F., Müller-Tidow C.: (2020) Site-specific methylation of 18S ribosomal RNA by SNORD42A is required for acute myeloid leukemia cell proliferation. BLOOD, 135: 2059-2070 32097467

 

2019

Harrach S., Barz V., Pap T., Pavenstädt H., Schlatter E., Edemir B., Distler J., Ciarimboli G., Bertrand J.: (2019) Notch Signaling Activity Determines Uptake and Biological Effect of Imatinib in Systemic Sclerosis Dermal Fibroblasts. JOURNAL OF INVESTIGATIVE DERMATOLOGY, 139: 439-447 30273596

Kandabarau S., Leiz J., Krohn K., Winter S., Bedke J., Schwab M., Schaeffeler E., Edemir B.: (2019) Hypertonicity-Affected Genes Are Differentially Expressed in Clear Cell Renal Cell Carcinoma and Correlate with Cancer-Specific Survival. Cancers, 12: E6 31861377

Schütte-Nütgen K., Edeling M., Mendl G., Krahn M.P., Edemir B., Weide T., Kremerskothen J., Michgehl U., Pavenstädt H.: (2019) Getting a Notch closer to renal dysfunction: activated Notch suppresses expression of the adaptor protein Disabled-2 in tubular epithelial cells. FASEB JOURNAL, 33: 821-832 30052485

Ziemens A., Sonntag S.R., Wulfmeyer V.C., Edemir B., Bleich M., Himmerkus N.: (2019) Claudin 19 Is Regulated by Extracellular Osmolality in Rat Kidney Inner Medullary Collecting Duct Cells. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 20: 1-10 31500238

 

2018

Betten R., Scharner B., Probst S., Edemir B., Wolff N.A., Langelueddecke C., Lee W.K., Thévenod F.: (2018) Tonicity inversely modulates lipocalin-2 (Lcn2/24p3/NGAL) receptor (SLC22A17) and Lcn2 expression via Wnt/β-catenin signaling in renal inner medullary collecting duct cells: implications for cell fate and bacterial infection. Cell Communication and Signaling, 16: 74 30404645

Comment/ Letter

Edemir B.: (2018) Considering hypertonicity in the interpretation and analysis of cell type-specific gene expression pattern in the collecting duct. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 115: E349-E350 29311340

 

2017

Harrach S., Edemir B., Schmidt-Lauber C., Pap T., Bertrand J., Ciarimboli G.: (2017) Importance of the novel organic cation transporter 1 for tyrosine kinase inhibition by saracatinib in rheumatoid arthritis synovial fibroblasts. Scientific Reports, 7: 1258 28455521

 

2016

Grabner A., Kentrup D., Pawelski H., Mühlmeister M., Biermann C., Edemir B., Heitplatz B., Van Marck V., Bettinger T., Pavenstädt H., Schlatter E., Stypmann J., Tiemann K., Reuter S.: (2016) Renal Contrast-Enhanced Sonography Findings in a Model of Acute Cellular Allograft Rejection. AMERICAN JOURNAL OF TRANSPLANTATION, 16: 1612-9 26613381

Harrach S., Schmidt-Lauber C., Pap T., Pavenstädt H., Schlatter E., Schmidt E., Berdel W.E., Schulze U., Edemir B., Jeromin S., Haferlach T., Ciarimboli G., Bertrand J.: (2016) MATE1 regulates cellular uptake and sensitivity to imatinib in CML patients. Blood Cancer Journal, 6: e470 27635733

Schulze Blasum B., Schröter R., Neugebauer U., Hofschröer V., Pavenstädt H., Ciarimboli G., Schlatter E., Edemir B.: (2016) The kidney-specific expression of genes can be modulated by the extracellular osmolality. FASEB JOURNAL, 30: 3588-3597

Vitavska O., Edemir B., Wieczorek H.: (2016) Putative role of the H(+)/sucrose symporter SLC45A3 as an osmolyte transporter in the kidney. PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY, 468: 1353-62 27228996