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Sarcomas of bone and soft tissues

Sarcomas of the bone and the soft tissues are relatively rare malignant tumors of mesenchymal origin. While they are relatively common in children and adolescents with 5-7% of all cancers, the incidence in adults is 2-3 new cases / year and 100,000 people. Soft tissue sarcomas occur predominantly in the extremities (legs more often than arms) , but one third are also sarcomas of the trunk, predominantly localized in the retroperitoneal space. Histologically, more than 20 groups of soft tissue sarcoma can be distinguished. Of the sarcomas of bone gain osteosarcoma, Ewing sarcoma, and the chondro sarcoma, this arises from cartilage tissue, the most important role. The diagnostic procedures include the histological confirmation, which is mainly provided by experts in the fields of orthopedics,  trauma and reconstructive surgery as well as by General and Visceral Surgery, the so-called "Staging diagnostics" (section imaging by CT Scan or MRI,  optionally in combination with FDG-PET or bone scintigraphy) for determining stages. While localized, non-metastatic soft tissue sarcomas are predominantly treated by orthopedic surgery, in the metastatic situation usually systemic chemotherapy (doxorubicin, ifosfamide, dacarbazine, gemcitabine, docetaxel) is indicated, as well as treatment with innovative substances such as trabectedin and pazopanib. In osteosarcomas the preoperative and postoperative therapy represents important pillars of the complete treatment concept with a potential curative intention. 

At our department a wide range of diagnostics and therapy of sarcomas from bone and soft tissue is offered in close cooperation with the Departments of Orthopedics and Traumatology and Reconstructive Surgery, General, Visceral and Vascular Surgery, Diagnostic Radiology, Nuclear Medicine as well as the Radiation Oncology. In the context of innovative study concepts promising new drugs can be used at an early stage. Patients will get individually and extensive information and we will coordinate and carried out the appropriate diagnostic and therapeutic steps. 

 

 

Contact

Prof. Dr. med.
Carsten Müller-Tidow
 

University Hospital Halle
Department for Internal Medicine IV
Hematology and Oncology
Ernst-Grube-Str. 40
D - 06120 Halle (Saale)
Phone: +49 345 557 2924
Fax: +49 345 557 2950
E-Mail: innere4©uk-halle.de